Estrogen is necessary for both women and men. In females it is primarily made in the ovaries. Estrogen levels can begin to decline as early as 35 years of age. By their fifties, most women begin to experience menopause. A personalized regimen of bio-identical hormone replacement therapy can significantly improve a woman’s overall quality of life.
With our personalized estrogen treatments, we see an improvement in all of these areas over time.
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We’ve observed that patients have fewer side effects with transdermal application. The risks of oral estrogens include elevated blood pressure, thrombosis, high triglycerides, and an increase in estrone. An increase in estrone increases the risk of breast and endometrial cancer. It can also elevate liver enzymes, decrease growth hormone, and increase sex hormone binding globulin that can reduce testosterone levels, resulting in weight gain.
Estradiol is the strongest of the three estrogens we will go over. It is the most active hormone during a woman’s reproductive years. Estradiol is required for reproductive and sexual functions and has an impact on the health of many other organs and tissues. This form of estrogen is regularly linked to gynecological disorders like fibroids and endometriosis in females.
Estrone is the least abundant estrogen of the three, and is created by abdominal fat cells. It is the main estrogen found in post-menopausal women who are not taking hormone replacement therapy. When compared to other estrogens, higher levels of estrone have been associated with cardiovascular disease, stroke, and certain types of cancer. This includes uterine and breast cancer. Estrone is often thought of as an estradiol precursor because it can be easily converted into estradiol. An imbalance of estrone or one of the other two major types of estrogens can increase the risk for many age-related diseases.
Estriol is the weakest of the three estrogens, yet it’s another form of estrogen metabolized from estradiol. This hormone is linked to pregnancy because it is produced in substantial amounts throughout this period. However, it is present throughout a woman’s lifetime at varying levels and has been shown to have anti-cancer effects by binding to estrogen receptors. This effectively decreases the estrogen activity in breast tissue.
Exercising and eating a high protein diet supplemented by Omega 3 fatty acids, B6, B12, and folate is key. Foods such as cruciferous vegetables, flax, rosemary, and turmeric have also been shown to raise estradiol levels.