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PEPTIDE TREATMENT

Also known as “secretagogues”, peptides are natural secretagogues of growth hormone. They stimulate the pituitary gland in the brain to pulsate and release natural growth hormone, but with different mechanisms. As we age, our growth hormone production slows down.  This process is known as somatopause).  With the help of these secretagogues you can stimulate the brains production to release just about the same amount of growth hormone produced in your early twenties.

 

GROWTH HORMONE & PEPTIDES

 

Growth hormone controls the reproduction and development of every cellular function in the human body.  This makes it invaluable for our health as we age. It is known as the “fountain of youth” or “master” hormone.  When we enter deep sleep or “REM” sleep, the pituitary gland releases a surge of growth hormone into the body.  By administering one of these peptides, you are drastically increasing and taping into your natural production. Now, you might be confused as to which peptide to administer, but no need to worry because All of this will be determined in detail by one of our Hormone Replacement Therapy physicians and based on your blood work results.

benefits of peptide treatments | hormone replacement therapy miami

INTERNATIONAL PEPTIDE SOCIETY CONFERENCE 2019

 

Thanks to the advancement of optimization medicine, we finally have the biotechnology to extend our lives and use biotechnology to reverse or control the effects of aging. Through peptides, we give the body the ability to do what it did well when we were younger, and give it that chance to do it well as we age. Peptides aren’t about cheating the health code or enhancing performance, they are about repairing and restoring our bodies. Every aspect of our bodies and our health can be completely changed by peptides.

 

We are at the forefront and cutting edge technology of the peptide society. We know it is the future of medicine, and we want to make sure we are forefront of this movement. Peptides have literally zero side effects and a ton of benefits. We recently attended the International Peptide Society Conference and had the pleasure of metting and speaking to Dr. William Seeds, who is the founder of the Peptide Society Conference . Check out the video of Michael Bertonatti at the conference!

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The following is a rundown of our peptide treatments program.  Peptide treatments are part of our Human Growth Hormone / HGH regiment.  We understand this is an important step for you and that the results you may have heard about or seen with your own eyes can be very enticing.  As they should be!!!  Human Growth Hormone / HGH protocols can make a world of difference in your livelihood! 

 

Although not required, we encourage all of our patients to educate themselves on all parts of our regiment in order to make the most accurate and conscious decision for your lifestyle.  

PEPTIDE TREATMENT & HORMONE REPLACEMENT THERAPY

IMMUNITY BOOSTING PEPTIDES

THYMOSIN ALPHA-1

 

A protein that consists of 28 amino acids. Thymosin Alpha-1 has been found to improve cell-mediated immunity in humans. Thymosin Alpha-1 plays a vital role in the control of immunity, tolerance, and inflammation. It manages immune response via an initial action on the cells of the innate immune system and thus acts as an endogenous regulator of both inflammatory and adaptive immune responses. Thymosin alpha-1’s immunomodulatory activities are centered primarily on the augmentation of T-cell function. Thymosin Alpha-1 has been used to treat diseases: Immune dysfunction, hepatitis B virus (HBV), hepatitis C virus (HCV), certain types of cancers, arthritis, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), chronic fatigue, lyme’s disease, HIV/AIDS, and autoimmune diseases.

PERFORMANCE & HEALING PEPTIDES

TESAMORELIN

What is Tesamorelin? Tesamorelin is a small molecule that stimulates the brain to produce growth hormone. It is a growth hormone-releasing hormone analog that increases IGF-1 levels in men and women, by an average of 181 micrograms/liter. This is by far the BEST & MOST EFFECTIVE peptide we’ve ever worked with. It binds to and stimulates GHRH receptors with similar potency as endogenous GHRH. It has a host of other benefits including nootropic effects and reducing triglycerides. Tesamorelin has subsequently been shown to decrease carotid intima-media thickness, visceral adipose tissue (VAT), and c-reactive protein (CRP). It has not been linked to significantly affect other pituitary hormones and their respective mechanisms in the body. Additionally, it can improve cognitive function for healthy seniors and patients with an increased risk of Alzheimer’s disease, due to mild cognitive impairment.

5-Amino-1MQ 

 

Is a small, selective membrane-permeable molecule that is an inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that plays a role in cellular metabolism and energy homeostasis. This NNMT inhibitor is being used to prevent adipogenesis (fat accumulation), type II diabetes, and reversing diet-induced obesity as a result of increased intracellular NAD + and SAM. As fat cells grow larger, they begin to overproduce an enzyme called NNMT (nicotinamide N-methyltransferase). This enzyme acts to slow down fat cell metabolism (fat burning). This slowdown makes it harder for these cells to burn accumulating fat. As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. The molecule 5-amino-1MQ blocks this metabolic slowdown in white fat cells caused by excess NNMT. By blocking this metabolic slowdown, it increases the metabolism within the white fat cells. By inhibiting the NNMT enzyme, we can increase fat cell metabolism and reduce the size of white fat deposits. We lose weight because we are treating the root cause of obesity and related metabolic disease.

IBUTAMOREN (MK-677)

 

Also known as Ibutamoren, it is a growth hormone secretagogue clinically shown to increase growth hormone and IGF-1 levels significantly.  It is safe to use because it doesn’t suppress the body’s natural ability to produce growth hormone.  The term secretagogue refers to any substance that triggers secretion of another substance.  In this case, the substance being secreted is growth hormone. Its main benefits in our biochemistry are increased muscle growth, decrease body fat and improve cognitive function.  In addition, Ibutamoren helps you sleep better, speeds up recovery, and slows aging down.

CJC 1295

 

A tetrasubstituted 30-amino acid peptide hormone, primarily functioning as a growth hormone releasing hormone (GHRH) analog. CJC 1295 has been shown to increase growth hormone in enormous amounts, but without side effects. CJC 1295 stimulates growth hormone secretion, and will keep a steady increase of HGH and IGF-1 with no increase in prolactin.  This leads to fat loss, and increased protein synthesis thereby promoting growth hormone.

 

One of the reasons CJC 1295 may be prescribed over traditional GHRH or HGH is its ability to bioconjugate with serum albumin, thus increasing its half-life and potential therapeutic window. It accomplishes this by using protecting groups around the amino acids of GHRH typically susceptible to enzymatic degradation.

IPAMORELIN

 

Ipamorelin is a selective GH-Secretagogue and ghrelin receptor agonist. The potency of ghrelin stimulation can be compared to GHRP6 with less appetite stimulation properties. However, unlike other growth hormone-secretagogues, this pentapeptide doesn’t release the same volumes of cortisol, acetylcholine, prolactin, and aldosterone. It is, for this reason, considered the first & best selective growth hormone-secretagogue.

IGF-1 LR3

 

Most often, IGF-1 LR3 (eighty-three amino acids) is used to stimulate muscle growth, and the compound significantly helps to make the body more sensitive to insulin, which in turn mobilizes fat for use as energy in adipose tissue. In lean tissue mass, IGF-1 LR3 prevents insulin from transporting glucose across cell membranes. As a result, the cells have to switch to burning off fat as a source of energy.

Cognitive nootropic BOOSTING PEPTIDES

FGL

 

FGL sparks synaptic plasticity, boosting memory and learning. In addition to its effects on neurodegenerative disease, it also has been viewed as a targeted treatment for TBI, stroke, depression, and general improvement of cognitive function.

 

SELANK (NOOTROPIC PEPTIDE)

 

Has been shown to improve the formation/storage of memory, learning process, and brain performance. Selank is also used as a treatment for depression, anti-anxiety, immune improvement,  and gastric protection.

 

DIHEXA

 

A nooptropic and a small peptide that has been developed by researchers from Washington State University to potently improve certain cognitive function of potential trauma-based brain disorders and neurodegenerative conditions such as Alzheimer’s through increased synaptogenesis. Dihexa is a peptide variant derived from angiotensin IV which has been found to improve cognitive function and diseases such as Alzheimer’s. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than BDNF “brain-derived neurotrophic factors.” It could help in the repair of the brain and nerves in neurological disease. Brain-derived neurotrophic factor (BDNF) serves as an essential regulatory mechanism in the growth and development of neurons in many areas of the brain. It has also been reported to play a part in improving the survival of neurons by heightening the resistance to nerve damage. Synaptogenesis is the formation of synapses between neurons in the nervous system. Although it occurs throughout a healthy persons’ lifespan, an explosion of synapse formation occurs during early brain development, known as exuberant synaptogenesis. Dihexa kind of mimics that response in our system.

 

SEMAX

 

Semax is used as a nootropic or cognitive enhancer. It has been shown to enhance memory performance, accelerated learning, increase in BDNF, and reduce the harmful effects of stress. Doctors prescribe it for many conditions like anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal, and even chronic diseases such as ALS, Parkinson’s, and Alzheimer’s.This peptide works significantly better in combination to the Selank peptide.

Cerebrolysin

 

Is a mixture of peptides and has been proven to have neurotrophic action similar to nerve growth factors, which cause peripheral and central neuronal stimulation. In other words, Cerebrolysin can improve cognitive function in older people with memory problems and in those with schizophrenia. Also, it improves efficiency within the brain’s aerobic metabolic processes and improves intracellular peptide synthesis. This peptide is recommended to do once a year for 30 days.

 

Epithalon

 

Also known as Epitalon or Epithalone, this is a polypeptide which is naturally produced in humans and has been shown to lengthen telomeres in human cells by activating the production of telomerase. In other words, if you want to ultimately slow down aging, then this is the peptide for you. Additionally, it restores and normalizes melatonin levels in older patients who have some loss in pineal function due to aging. This peptide is recommended to do once a year for 80 days.

 

Melanotan I and Melanotan II

 

Are both analogs of the peptide hormone alpha-melanocyte- stimulating hormone (α-MSH) that induces skin tanning and is used as a cognitive anti-inflammatory remedy to protect the brain from battering aging. Like its predecessor, Melanotan I, MT2 plays a role in stimulating melanogenesis and thus provides a protective mechanism against UV rays since under its actions melanocytes are able to increase production and secretion of the hormone melanin. Scientists have also noticed that Melanotan 2 had a positive effect on libido due to its aphrodisiac properties. Additionally, Melanotan 2 exhibits a mild positive fat-mobilizing effect. Melanotan I is an FDA approved drug under the brand name Scenesse. Scenesse is most commonly used to treat patients that have an intolerance to light.

INJURY & RECOVERY PEPTIDES

BPC-157

 

Body Protecting Compound 157 (BPC 157) has demonstrated to accelerate the healing of many different wounds, including tendon-to-bone healing and superior healing of damaged ligaments. This peptide (composed of fifteen amino acids) is also shown to decrease pain in damaged areas. Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide. It can also help aid skin burns to heal at a faster rate and increase blood flow to damaged tissues.

Thymosin Beta 4

 

TB4 is a hormone, and its primary function is to stimulate the production of T-cells, which are an essential part of the immune and used mainly for acute injuries, and surgical repair.

Libido & sexual performance peptides

PT-141

 

Unlike Viagra and other related PDE5 inhibitor medications, this peptide medication does not act upon the vascular system but directly increases sexual desire via the nervous system. It treats sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

SLEEP INDUCING PEPTIDES

DSIP

 

Also known as delta sleep inducing peptide, it is a peptide that produces a deep state of sleep. It was primarily involved in sleep regulation due to its ability to induce slow-wave sleep and can normalize blood pressure and myocardial contraction. We suggest taking this peptide five nights a week and two nights off a week to avoid a diminishing response for sleep because if its high attrition rate.

OLDER KNOWN PEPTIDES (LEAST COMMONLY USED)

Sermorelin

 

is a secretagogue of growth hormone made of 29 amino acids. It stimulates the brain’s hypothalamus. The human hypothalamus is a gland in the brain adjacent to the pituitary gland. The pituitary gland releases the actual growth hormone into your body. As we get older, the growth hormone produced by the anterior pituitary begins to deplete. It has now been shown that Sermorelin can restore growth hormone to a youthful level causing an array of health benefits.

 

Growth hormone releasing peptide 2 (GHRP-2)

 

Also known as GHRP-2, Growth Hormone releasing Peptide 2 is a peptide is made up of just six amino acids. These amino acids stimulates secretion of endogenous GH. Research shows GHRP-2 can stimulate the pituitary to increase secretion of growth hormone by 7-15 times. Thus, stimulating ghrelin receptors to promote appetite. GHRP-2 acts as a synthetic ghrelin analog. This is why it stimulates the release of an endogenous growth hormone within the somatotropes of the anterior pituitary. Specifically, GHRP-2 will increase the number of somatotropes in a GH pulse by limiting the amount of somatostatin present. Concurrently, the standard GHRH increases the amplitude at which the pituitary cells pulse.

 

Growth hormone releasing peptide 6

 

(GHRP-6) is not an active fragment of growth hormone releasing hormone (GHRH). It is one of several synthetic met-enkephalin analogs that include unnatural D-amino acids. GHRP 6 is a true hGH secretagogue, which means it stimulates the body’s own secretion of Human Growth Hormone. HGH has been shown in studies to promote lean body mass and reduce adiposity (fat). It is now known that these growth hormone releasing peptides are distinct from GHRH and do not act at the GHRH receptor, but instead act at the growth hormone secretagogue receptor. This receptor is now renamed as the ghrelin receptor. It is for this reason (gherlin like properties) patients being treated with GHRP 6 experience appetite stimulation. In therapy GHRP 6 is used to stimulate growth hormone production while increasing body mass. Patients deficient in growth hormone and underweight would be ideal candidates for GHRP 6.

COMMON SIGNS & SYMPTOMS LOW HUMAN GROWTH HORMONE / HGH

LEVELS

  • Saggy muscles & skin
  • Drastic Increase in wrinkles and skin elasticity
  • Memory loss
  • Poor mental function and concentration
  • Diminished quality in sleep
  • Increase in body fat, especially around the midsection
  • Weak joints & bones
  • Poor wound healing
  • Organ malfunction
  • Reduce Visibility
  • Crohns Disease
  • Cancer
  • Diabetes

RESULTS AFTER PEPTIDE TREATMENT

With our personalized peptide secretagogue therapies, our patients report an improvement in many or all of these areas over time.

BOOK YOUR PEPTIDE TREATMENT CONSULTATION TODAY!!!

 

MIAMI HORMONE REPLACEMENT THERAPY SPECIALISTS

FREQUENTLY ASKED QUESTIONS

HOW DO I TAKE THESE PEPTIDES?

During peptide treatment, peptides are injected into the body fat, subcutaneously.  This is done using the smallest needle available, similar to what a person with diabetes uses to inject insulin.  Injections are initially prescribed to inject every night and over time, are decreased in frequency. However, this will be assessed by one of our medical directors.

DO OTHER PEPTIDES LIKE GHRP-2 & 6 WORK BETTER WITH SERMORELIN TREATMENT?

Yes and no. 5 out of 10 patients experience side effects like uncontrollable hunger pangs, hot flashes, sleepiness, and headaches with GHRP’S. The other five, report significant better results with the combination of Sermorelin & GHRP peptides.

HOW LONG DOES IT TAKE BEFORE MY PEPTIDE TREATMENT STARTS WORKING?

Peptides, like HGH, is excreted from the body very quickly so it must be injected on a nightly basis. The benefits can be seen as early as eight weeks into the peptide treatment.  But initial and almost immediate benefits include better sleep, mental sharpness, and memory retention. However, to experience complete physical effects, these medications during peptide treatment should be taken continuously for six months.

WILL I HAVE TO TAKE A PEPTIDE TREATMENT FOREVER?

Yes and no. Once optimal growth hormone levels are achieved, they can be sustained for a long time after final injection. We’ve only seen this, if weight resistance training and a healthy diet are implemented along with the patient’s peptide treatment.

 

For those who are not as active or lucky, once results are achieved, patients are then switched to a maintenance protocol.  Thus, eliminating the need for ongoing nightly injections and reducing the total cost of therapy. However, this will be determined through follow-up blood work and the patient’s feedback during peptide treatment.

CAN I OVERDOSE FROM ANY OF THESE PEPTIDE TREATMENTS?

No. In comparison to injectable Human Growth Hormone / HGH, peptides are safer, more affordable, and can be just as effective. Our endocrine system can safely regulate (through a negative feedback loop) the amount of growth hormone released by the pituitary gland. This results in zero overload to the system, increased safety and prevention of side effects.  You cannot overdose from peptide treatments.

ARE DOSAGES OF HUMAN GROWTH HORMONE / HGH AND PEPTIDE COMPARABLE?

Although they work on different sites in the body, Human Growth Hormone / HGH acts on the liver .  Conversely, peptides act on the pituitary and/or hypothalamus gland, the amount of each needed to be effective is approximately the same.

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